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There are no limits on a particular ERF object containing objects. The game now successfully reads all objects into the game properly. This means that you can safely have all areas, scripts and blueprints in the module file as usual, and other things like models, effects and 2da files in hakpacks.
Note: Hakpack files should stay under 2GB since the Toolset (and other tools like nwsync) doesn't read past 2GB.
Anything Earlier than 1.80.8193.14 (including NWN Diamond)
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See this discussion: https://forums.beamdog.com/discussion/66993/toolset-resource-limit
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Palette Limits
There was previously in 1.69 and earlier a pallet palette size limit of 1MB for the DM palletpalette. It takes a lot to fill this - but funnily enough it's on average 16K entries. This is fixed in NWN:EE and pallet palette sizes can be a lot bigger so go nuts.