At least for some cases it is possible to add/replace sounds.
I. Placeable- and door-sounds
The availabe sounds are in the placeableobjsnds.2da (here: 34.1):
...
mydoor_op(en)/cl(ose) are 16 bit mono sounds (edited with Audacity)
genericdoors.2da:
Label StrRef ModelName BlockSight VisibleModel SoundAppType Name
...
StrRef = Line in the dialog.tlk (in ths this case "door")
II. ... (mybe creature sounds?)